Peptides in Skincare — What It Does and How to Use It

Peptides are short chains of amino acids — the building blocks of proteins including collagen, elastin, and keratin. In skincare, specific peptide sequences act as biological messengers, signalling the skin to produce more collagen, repair the barrier, or relax facial tension.

Best for

Anti-Ageing, Firming, Barrier Repair

Typical concentration

Varies by peptide type

Works well with

Hyaluronic Acid, Niacinamide, Ceramides — most actives

Use caution with

Avoid layering directly with AHAs at low pH — may reduce efficacy

What it does

Signal peptides (such as Matrixyl/palmitoyl pentapeptide-4) trigger collagen and hyaluronic acid production. Carrier peptides (such as copper peptides) deliver trace minerals that activate wound-healing enzymes. Neurotransmitter peptides (such as Argireline) reduce the appearance of expression lines by limiting muscle contraction. K-beauty brands have been early adopters — the COSRX 6 Peptide Booster Serum combines multiple peptide types for a synergistic anti-ageing effect.

How to use it

Apply after toning, before moisturiser. No pH requirements. Unlike retinoids or acids, peptides can be used morning and evening without adjustment periods or sun sensitivity concerns. Avoid layering directly on top of acidic toners — allow pH to normalise first.

Who is it suitable for?

All skin types including sensitive and pregnant skin. Suitable for all ages as a preventative or corrective treatment.

Products containing Peptides

References

[1] Gorouhi F & Maibach HI. Role of topical peptides in preventing or treating aged skin. IJCS. 2009.
[2] Pai VV et al. Peptides and proteins: skin care and cosmetic applications. J Cosmet Dermatol. 2017.

Peptides: What It Does and How to Use It

What it does

How to use it

Who is it suitable for?

Products containing Peptides

References