Niacinamide: What It Does and How to Use It

What it does

Niacinamide works through several mechanisms simultaneously. It is a precursor to NAD+ and NADP+ — coenzymes essential to cellular energy metabolism and DNA repair. It reduces melanin transfer between cells, visibly fading hyperpigmentation and post-inflammatory marks. It stimulates ceramide synthesis, strengthening the skin barrier. It reduces sebum production, making it particularly useful for oily and combination skin. A 2002 study by Bissett et al demonstrated significant reduction in hyperpigmentation, fine lines, and yellowing after 12 weeks of topical application.

How to use it

Apply after toning and before heavier serums or moisturiser. Niacinamide has no pH requirements — it works at cosmetic pH and does not need to be applied to freshly cleansed skin. If using Vitamin C, apply Vitamin C first, allow it to absorb for a few minutes, then apply niacinamide. Start at 5% if new to the ingredient.

Who is it suitable for?

All skin types including sensitive. Particularly effective for combination and oily skin (sebum control) and for hyperpigmentation.

Products containing Niacinamide

References

[1] Bissett DL et al. Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatol Surg. 2005.
[2] Tanno O et al. Nicotinamide increases biosynthesis of ceramides. Br J Dermatol. 2000.